I used to swear by the Chinatown bus. Back when I first met my wife, we had a long-distance relationship (she was in NYC, I was here), and I'd generally take that up every other weekend to see her. I never minded the people, and the convenience was great...
Until one ill fated trip where I made the mistake of switching seats with some female college students that wanted to sit together. Between having to listen to their inane conversation THROUGH my headphones, and having an ENORMOUS dude in front of my put his seat back in full recline the entire trip and being right next to the bathroom which had obviously not been emptied in quite a while, I swore it off forever.
Fuck the ozone...I drive from now one.