the EF is really, really big - think a huge warehouse with a stage at one end. i'm not a big fan of the place, but it's not horrible either. sounds has been good all 3 times i've been there. the dandys won't come close to filling the place so shouldn't be too bad. sold-out shows are a real pain there.
neighborhood is industrial/warehouse/scene gang fight in a movie (not that i've ever seen gangs there, it's always deserted). on a show night you'll be fine parking nearby and walking to the venue, but it's not somewhere you'd hang otherwise. chinatown is close by, hang there instead and drive over to the venue when ready to enter.